Akintunde Adeseye A, Familoni Oluranti B, Akinwusi Patience O, Opadijo O George
Division of Cardiology, Lautech Teaching Hospital, Osogbo, Osun State, Nigeria.
Cardiovasc J Afr. 2010 Jan-Feb;21(1):21-5.
Despite a high worldwide prevalence of left ventricular hypertrophy among black patients, the association of a specific left ventricular geometric pattern with left ventricular dysfunction is rare. The aim of this study was to explore the possibility of such an association in Nigerian hypertensives.
This was a retrospective study consisting of 188 treated hypertensives. Echocardiography was used to allocate the patients to the following four groups: normal geometric pattern, concentric remodelling, eccentric hypertrophy and concentric hypertrophy.
The mean age of the study population was 55.95 +/- 10.71 years. There were 75 females (39.9%). Concentric hypertrophy occurred in 72 (38.3%) patients and concentric remodelling in 53 (28.2%). Only 30 (16%) had a normal left ventricular geometric pattern. Hypertensive subjects with eccentric hypertrophy had the lowest ejection fraction, fractional fibre shortening and left ventricular ejection time but these did not reach statistical significance. The mean left atrial dimension was highest in the subjects with eccentric hypertrophy.
In this study population of treated Nigerian hypertensives, concentric remodelling and hypertrophy were the predominant left ventricular geometrical patterns.
尽管全球黑人患者左心室肥厚的患病率很高，但特定的左心室几何形态与左心室功能障碍之间的关联却很少见。本研究的目的是探讨尼日利亚高血压患者中这种关联的可能性。
这是一项回顾性研究，包括188例接受治疗的高血压患者。使用超声心动图将患者分为以下四组：正常几何形态、向心性重构、离心性肥厚和向心性肥厚。
研究人群的平均年龄为55.95±10.71岁。有75名女性（39.9%）。72例（38.3%）患者出现向心性肥厚，53例（28.2%）出现向心性重构。只有30例（16%）左心室几何形态正常。离心性肥厚的高血压患者射血分数、纤维缩短分数和左心室射血时间最低，但未达到统计学意义。离心性肥厚患者的平均左心房内径最大。
在本研究的尼日利亚高血压患者群体中，向心性重构和肥厚是主要的左心室几何形态。
