Department of Medicine, LadokeAkintola University of Technology & LAUTECH Teaching Hospital, Ogbomoso, Nigeria.
Goshen Heart Clinic, Osogbo, Nigeria.
Afr Health Sci. 2022 Jun;22(2):257-263. doi: 10.4314/ahs.v22i2.29.
Left atrial enlargement (LAE) predispose to arrhythmias, atrial thrombogenesis and cardioembolic stroke. Whether LAE constitute a major risk among African hypertensive subjects is not well described. This study was aimed to describe the epidemiologic pattern of LAE among hypertensive subjects and determine their correlates.
Clinical and demographic details of 414 hypertensive subjects used were taken. Echocardiography was done. LAE was defined as Left atrial dimension (LAD)>3.7 cm. Statistical analysis was done using SPSS 17.0.
414 subjects including 258 (62.3%) males were recruited. The mean age was 56.8±16.8 years. LAE was present in 57.73% of hypertensive subjects. Those with LAE were likely to be older (58.23±14.5 vs. 54.8 ±19.7 years, p<0.05), had a higher waist circumference (88.1 ±26.8 ±75.8 ±28.4 cm, p<0.05), left ventricular mass index (79.2 ± 12.4 vs. 48.7 ±15.5g/m2.7, p<0.05) and a higher frequency of left ventricular hypertrophy (LVH) (65.3% vs. 40.0 %, p<0.05) respectively than those without LAE. LAD was significantly higher among those with LVH than those without LVH (41.4 ±8.4 vs. 35.6 ±5.9 mm respectively, p<0.05).
LAE is common among Nigerian hypertensive subjects. Age, waist circumference, left ventricular wall dimension and mass index are the important correlates of LAE in hypertensive Nigerians.
左心房扩大（LAE）易导致心律失常、心房血栓形成和心源性脑栓塞。LAE 是否是非洲高血压患者的主要风险因素尚不清楚。本研究旨在描述高血压患者中 LAE 的流行病学模式，并确定其相关因素。
纳入了 414 名高血压患者的临床和人口统计学资料。进行了超声心动图检查。LAE 定义为左心房内径（LAD）>3.7cm。使用 SPSS 17.0 进行统计分析。
共纳入 414 名患者，其中 258 名（62.3%）为男性，平均年龄为 56.8±16.8 岁。57.73%的高血压患者存在 LAE。LAE 患者年龄较大（58.23±14.5 岁 vs. 54.8±19.7 岁，p<0.05），腰围较大（88.1±26.8cm vs. 75.8±28.4cm，p<0.05），左心室质量指数较高（79.2±12.4g/m2.7 vs. 48.7±15.5g/m2.7，p<0.05），左心室肥厚（LVH）发生率较高（65.3% vs. 40.0%，p<0.05）。与无 LVH 患者相比，LVH 患者的 LAD 明显更高（41.4±8.4mm vs. 35.6±5.9mm，p<0.05）。
LAE 在尼日利亚高血压患者中较为常见。年龄、腰围、左心室壁厚度和质量指数是尼日利亚高血压患者 LAE 的重要相关因素。
