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[专利蓝V:惰性染料还是强效过敏原?]

[Patent blue V : inert dye or potent allergen].

作者信息

Rogler V, Röhm C, Reutershan J

机构信息

Klinik für Anaesthesiologie und Intensivmedizin, Universitätsklinikum Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Deutschland.

出版信息

Anaesthesist. 2010 May;59(5):423-6. doi: 10.1007/s00101-010-1700-3.

DOI:10.1007/s00101-010-1700-3
PMID:20224949
Abstract

Patent blue V is widely used as a food dye. Clinically, patent blue V dye has been increasingly used in oncological surgery to identify the sentinel lymph nodes in breast cancer and other malignancies. The case of a patient who developed severe anaphylactic shock to subcutaneous injection of patent blue V during breast surgery is presented. The clinical course and the anesthesiological management are presented, and the pitfalls that may delay the correct diagnosis are highlighted.

摘要

专利蓝V被广泛用作食品染料。临床上,专利蓝V染料在肿瘤外科手术中越来越多地用于识别乳腺癌和其他恶性肿瘤的前哨淋巴结。本文介绍了一例在乳腺手术期间皮下注射专利蓝V后发生严重过敏性休克的患者病例。介绍了临床过程和麻醉管理,并强调了可能延误正确诊断的陷阱。

相似文献

1
[Patent blue V : inert dye or potent allergen].[专利蓝V:惰性染料还是强效过敏原?]
Anaesthesist. 2010 May;59(5):423-6. doi: 10.1007/s00101-010-1700-3.
2
Patients blue on patent blue: an adverse reaction during four sentinel node procedures.注射专利蓝后皮肤变蓝的患者:4例前哨淋巴结手术中的不良反应
Surg Oncol. 2005 Dec;14(4):151-4. doi: 10.1016/j.suronc.2005.12.001. Epub 2006 Feb 10.
3
[Allergic reaction to patent blue dye for sentinel lymph node detection during uterus oncological surgery].
Ann Fr Anesth Reanim. 2005 May;24(5):541-2. doi: 10.1016/j.annfar.2005.02.025. Epub 2005 Apr 8.
4
A Case of Anaphylaxis to Patent Blue in a Patient with Sentinel Lymph Node Excision.一例前哨淋巴结切除患者对专利蓝过敏的病例
Iran J Allergy Asthma Immunol. 2016 Dec;15(6):547-550.
5
Severe anaphylactic shock to Patent Blue V with cardiac arrest during breast carcinoma surgery with lymphatic mapping.在乳腺癌手术及淋巴绘图过程中,对专利蓝V发生严重过敏反应并导致心脏骤停。
Eur J Obstet Gynecol Reprod Biol. 2008 Sep;140(1):140-1. doi: 10.1016/j.ejogrb.2007.09.008. Epub 2007 Oct 29.
6
Anaphylaxis and patent Blue V.
Anaesth Intensive Care. 2011 Jul;39(4):758; author reply 760.
7
Anaphylaxis to patent blue dye during sentinel lymph node biopsy for breast cancer.
Eur J Surg Oncol. 2001 Mar;27(2):218-9. doi: 10.1053/ejso.2000.1030.
8
Anaphylaxis to patent blue dye--the benefit and the risk.对专利蓝染料的过敏反应——益处与风险
Anaesth Intensive Care. 2011 Jul;39(4):758-60; author reply 760.
9
Anaphylactic reaction to patent blue V after sentinel lymph node biopsy.前哨淋巴结活检后对专利蓝V的过敏反应。
Acta Anaesthesiol Scand. 2006 Feb;50(2):245-7. doi: 10.1111/j.1399-6576.2006.00912.x.
10
[Anaphylactic shock due to "patent blue" used to search for the sentinel node].[因用于寻找前哨淋巴结的“专利蓝”导致的过敏性休克]
J Gynecol Obstet Biol Reprod (Paris). 1999 Jul;28(4):393-4.

本文引用的文献

1
Adverse reactions to patent blue V dye - The NEW START and ALMANAC experience.专利蓝 V 染料的不良反应——NEW START 和 ALMANAC 研究经验。
Eur J Surg Oncol. 2010 Apr;36(4):399-403. doi: 10.1016/j.ejso.2009.10.007. Epub 2009 Nov 24.
2
Anaphylaxis to patent blue V: a case series and proposed diagnostic protocol.专利蓝 V 过敏:病例系列及诊断方案建议。
Allergy. 2010 Mar;65(3):396-400. doi: 10.1111/j.1398-9995.2009.02248.x. Epub 2009 Nov 20.
3
Trastuzumab (Herceptin)-associated cardiomyopathy presented as new onset of complete left bundle-branch block mimicking acute coronary syndrome: a case report and literature review.
曲妥珠单抗(赫赛汀)相关的心肌病表现为新发完全性左束支传导阻滞,酷似急性冠状动脉综合征:一例报告及文献复习
Am J Emerg Med. 2009 Sep;27(7):903.e1-3. doi: 10.1016/j.ajem.2008.11.012.
4
[Immediate patent blue-induced hypersensitivity during sentinel node detection: The value of cutaneous tests].[前哨淋巴结检测期间即刻专利蓝诱导的超敏反应:皮肤试验的价值]
Ann Dermatol Venereol. 2008 Jun-Jul;135(6-7):461-5. doi: 10.1016/j.annder.2007.12.017. Epub 2008 Jun 19.
5
Anaphylaxis to dyes during the perioperative period: reports of 14 clinical cases.围手术期对染料的过敏反应:14例临床病例报告
J Allergy Clin Immunol. 2008 Aug;122(2):348-52. doi: 10.1016/j.jaci.2008.04.040. Epub 2008 Jun 12.
6
Patent blue sentinel node mapping in cervical cancer patients may lead to decreased pulse oximeter readings and positive methaemoglobin results.专利蓝示踪淋巴结图谱在宫颈癌患者中可能导致脉搏血氧饱和度读数降低和高铁血红蛋白结果呈阳性。
Eur J Anaesthesiol. 2008 May;25(5):365-8. doi: 10.1017/S0265021508003578. Epub 2008 Feb 13.
7
Severe anaphylactic shock to Patent Blue V with cardiac arrest during breast carcinoma surgery with lymphatic mapping.在乳腺癌手术及淋巴绘图过程中,对专利蓝V发生严重过敏反应并导致心脏骤停。
Eur J Obstet Gynecol Reprod Biol. 2008 Sep;140(1):140-1. doi: 10.1016/j.ejogrb.2007.09.008. Epub 2007 Oct 29.
8
[Medical emergencies following dermatological injections and infusions].[皮肤科注射和输液后的医疗紧急情况]
Hautarzt. 2006 Mar;57(3):195-201. doi: 10.1007/s00105-006-1107-x.
9
Anaphylactic reaction to patent blue V after sentinel lymph node biopsy.前哨淋巴结活检后对专利蓝V的过敏反应。
Acta Anaesthesiol Scand. 2006 Feb;50(2):245-7. doi: 10.1111/j.1399-6576.2006.00912.x.
10
A comparison of the adverse reactions associated with isosulfan blue versus methylene blue dye in sentinel lymph node biopsy for breast cancer.异硫蓝与亚甲蓝染料在乳腺癌前哨淋巴结活检中相关不良反应的比较。
Am J Surg. 2005 Feb;189(2):236-9. doi: 10.1016/j.amjsurg.2004.06.042.