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养老院中痴呆症神经精神症状的药物治疗:精神科门诊与基层医疗精神科医生服务提供情况的比较

[Pharmacotherapy of neuropsychiatric symptoms in dementia in nursing homes: a comparison of service provision by psychiatric outpatient clinics and primary care psychiatrists].

作者信息

Rapp Michael A, Majic Tomislav, Pluta Jan-Paul, Mell Thomas, Kalbitzer Jan, Treusch Yvonne, Heinz Andreas, Gutzmann Hans

机构信息

Klinik für Psychiatrie und Psychotherapie, Charité Campus Mitte, Berlin.

出版信息

Psychiatr Prax. 2010 May;37(4):196-8. doi: 10.1055/s-0029-1223475. Epub 2010 Mar 11.

Abstract

BACKGROUND

Neuropsychiatric symptoms of dementia like agitation, depression and apathy often result in increased prescriptions of psychotropics. In Germany, outpatient clinics at psychiatric hospitals play an important role in the treatment of neuropsychiatric symptoms in nursing homes. The aim of this study was to test whether the severity and pharmacotherapy differed in patients treated by outpatient clinics at psychiatric hospitals, as compared to primary care specialists.

METHODS

A cross-sectional study of the prevalence of agitation, apathy, and depression, and the amount of psychotropics prescribed in defined daily dosages (DDD) in 304 residents with dementia in 18 Berlin nursing homes.

RESULTS

Patients treated by outpatient clinics at psychiatric hospitals suffered from more severe neuropsychiatric symptoms (p < 0.05), were prescribed more antidepressants and antidementia agents (p < 0.05) and, when adjusting for the severity of agitation, less neuroleptics (p < 0.05) as compared to primary care specialists.

CONCLUSION

Psychiatric outpatient clinics at hospitals treat more severely demented patients who suffer from severe neuropsychiatric symptoms. The pharmacotherapy provided by these clinics displays a favourable profile according to established treatment guidelines.

摘要

背景

痴呆的神经精神症状,如激越、抑郁和淡漠,常常导致精神药物处方量增加。在德国,精神病医院的门诊诊所在养老院神经精神症状的治疗中发挥着重要作用。本研究的目的是检验与初级保健专科医生相比,在精神病医院门诊诊所接受治疗的患者其症状严重程度和药物治疗是否存在差异。

方法

对柏林18家养老院中304例痴呆患者的激越、淡漠和抑郁患病率以及按限定日剂量(DDD)开具的精神药物处方量进行横断面研究。

结果

与初级保健专科医生相比,在精神病医院门诊诊所接受治疗的患者患有更严重的神经精神症状(p < 0.05),被开具更多的抗抑郁药和抗痴呆药(p < 0.05),并且在对激越严重程度进行校正后,开具的抗精神病药较少(p < 0.05)。

结论

医院精神病门诊诊所治疗的痴呆患者病情更严重,且患有严重的神经精神症状。根据既定的治疗指南,这些诊所提供的药物治疗显示出良好的效果。

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