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荷兰大量痴呆症养老院患者中神经精神症状的患病率。

Prevalence of neuropsychiatric symptoms in a large sample of Dutch nursing home patients with dementia.

作者信息

Zuidema Sytse U, Derksen Els, Verhey Frans R J, Koopmans Raymond T C M

机构信息

Kalorama, Beek-Ubbergen, The Netherlands.

出版信息

Int J Geriatr Psychiatry. 2007 Jul;22(7):632-8. doi: 10.1002/gps.1722.

Abstract

OBJECTIVE

To estimate the prevalence of neuropsychiatric symptoms of dementia patients in Dutch nursing homes.

METHODS

Cross-sectional study in a large sample of 1322 demented patients living in 59 dementia special care units (SCUs) in The Netherlands. Symptoms were observed by licensed vocational nurses during regular care-giving in a 2-week observational period prior to assessment. Neuropsychiatric symptoms were assessed using the Neuropsychiatric Inventory- Nursing home version (NPI-NH; frequency X severity score >/= 4) and the Cohen-Mansfield Agitation Inventory (CMAI; symptoms occurring at least once a week).

RESULTS

More than 80% of these patients suffered from at least one clinically significant symptom, as defined with the NPI-NH frequency X severity score >/= 4. Measured with the NPH-NH agitation/aggression, apathy and irritability were the most frequently observed behaviors, with prevalences of 30-35%. Using the CMAI, 85% of the patients showed at least one symptom of agitation, of which general restlessness was observed most frequently (44%). Other frequently observed symptoms with prevalence rates of 30% were cursing or verbal aggression, constant request for attention, negativism, repetitious sentences, mannerisms, pacing, and complaining. Physically aggressive symptoms such as hitting, kicking, biting occurred less often (less than 13%).

CONCLUSIONS

Prevalence rates of neuropsychiatric symptoms in Dutch nursing home patients with dementia residing in SCUs are high, especially agitation and apathy. Insight into the prevalence rates of individual symptoms in patients with dementia has important practical consequences for the accurate planning of staff allotment and stresses the need for patient oriented care.

摘要

目的

评估荷兰养老院中痴呆患者神经精神症状的患病率。

方法

对荷兰59个痴呆症特殊护理单元(SCU)中的1322名痴呆患者进行大样本横断面研究。在评估前的2周观察期内,由持牌职业护士在常规护理过程中观察症状。使用神经精神科问卷-养老院版(NPI-NH;频率×严重程度评分≥4)和科恩-曼斯菲尔德激越量表(CMAI;症状每周至少出现一次)评估神经精神症状。

结果

超过80%的这些患者患有至少一种具有临床意义的症状,这是根据NPI-NH频率×严重程度评分≥4定义的。用NPH-NH评估,激越/攻击行为、冷漠和易怒是最常观察到的行为,患病率为30%-35%。使用CMAI,85%的患者表现出至少一种激越症状,其中普遍坐立不安最为常见(44%)。其他患病率为30%的常见症状包括咒骂或言语攻击、不断寻求关注、消极态度、重复语句、怪癖、踱步和抱怨。身体攻击症状如殴打、踢打、咬人则较少见(不到13%)。

结论

居住在SCU中的荷兰养老院痴呆患者神经精神症状的患病率很高,尤其是激越和冷漠。了解痴呆患者个体症状的患病率对于准确规划人员分配具有重要的实际意义,并强调了以患者为导向的护理的必要性。

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