Division of Genetics, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.
Pediatr Neonatol. 2010 Feb;51(1):57-60. doi: 10.1016/S1875-9572(10)60011-3.
Cerebro-costo-mandibular syndrome (CCMS) consists of severe micrognathia, glossoptosis, posterior rib-gap defects and developmental delay. It may cause upper airway obstruction andflail chest, resulting in neonatal hypoxia, and possibly death. Early airway management or surgical intervention to maintain a patent airway is critical to avoid hypoxia in CCMS patients. We report a newborn with CCMS who was successfully weaned from a laryngeal mask after undergoing a tongue-lip adhesion operation at 164 days of age.
脑-肋-颌综合征（CCMS）由严重的小颌畸形、舌下垂、后肋间隙缺损和发育迟缓组成。它可能导致上呼吸道阻塞和连枷胸，导致新生儿缺氧，甚至死亡。早期气道管理或手术干预以保持气道通畅对于避免 CCMS 患者缺氧至关重要。我们报告了一例 CCMS 新生儿，在 164 天时接受舌唇粘连手术后，成功地从喉罩中撤机。
