利用乳球菌生产人生长激素。

Production of human growth hormone by Lactococcus lactis.

机构信息

Departamento de Microbiología y Bioquímica de Productos Lácteos, Instituto de Productos Lácteos de Asturias (CSIC), Carretera de Infiesto s/n 3300 Villaviciosa, Asturias, Spain.

出版信息

J Biosci Bioeng. 2010 Apr;109(4):322-4. doi: 10.1016/j.jbiosc.2009.10.006. Epub 2009 Oct 27.

DOI:10.1016/j.jbiosc.2009.10.006

PMID:20226370

Abstract

A synthetic gene coding for human growth hormone was expressed in Lactococcus lactis. The presence of the recombinant protein was assayed and quantified using ELISA tests. Human growth hormone was detected at high concentrations and displayed a biological activity similar to the one shown by commercial human growth hormone.

摘要

一种编码人生长激素的合成基因在乳酸乳球菌中得到了表达。使用 ELISA 试验检测和定量了重组蛋白的存在。检测到了高浓度的人生长激素，并且其生物活性与商业人生长激素相似。