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麻醉专业化为大血管手术后的早期和中期生存提供了改善。

Anaesthetic specialisation leads to improved early- and medium-term survival following major vascular surgery.

机构信息

Norfolk & Norwich Vascular Unit, Norfolk & Norwich University Hospital, Colney lane, Norwich NR4 7UY, United Kingdom.

出版信息

Eur J Vasc Endovasc Surg. 2010 Jun;39(6):719-25. doi: 10.1016/j.ejvs.2010.02.004. Epub 2010 Mar 11.

Abstract

OBJECTIVE

Vascular surgical specialisation is associated with improved outcomes. We aimed to assess the effect of anaesthetic specialisation on outcome following major vascular surgery.

DESIGN

Retrospective cohort study.

METHODS

Patients undergoing major vascular surgery (lower limb revascularisation, elective and ruptured abdominal aortic aneurysm repair, endovascular aneurysm repair and carotid endarterectomy) over a five-year period were identified from a prospective database. The primary outcomes were death within 30 days and death within two years of surgery. Potential risk factors for mortality were assessed using multivariate logistic regression modelling.

RESULTS

The analysis cohort comprised 1155 patients followed up for a median of 583 days. Mortality within two years of surgery was 16%. For the overall cohort, care from vascular anaesthetists was independently associated with reduced 30-day (odds ratio 0.22; 95% CI 0.12-0.62) and medium-term mortality (0.31; 95% CI 0.18-0.55). For elective patients (n=851), vascular anaesthesia reduced two-year mortality (odds ratio 0.29; 95% CI 0.15-0.58; P=0.0004) though not 30-day mortality (odds ratio 0.55; 95% CI 0.15-1.95; P=0.35). For emergency patients, care by a vascular anaesthetist influenced neither 30-day mortality (odds ratio 0.33; 95% CI 0.08-1.41; P=0.13) nor medium-term mortality (odds ratio 0.45; 95% CI 0.17-1.21; P=0.11).

CONCLUSIONS

Anaesthetic specialisation reduced early- and medium-term mortality rates following major vascular surgery. If replicated by prospective studies, these results suggest that vascular surgery services would benefit from specialised anaesthetic support.

摘要

目的

血管外科专业与改善结果相关。我们旨在评估麻醉专业对大血管手术后结果的影响。

设计

回顾性队列研究。

方法

从一个前瞻性数据库中确定了在五年期间接受大血管手术(下肢血运重建术、择期和破裂性腹主动脉瘤修复术、血管内动脉瘤修复术和颈动脉内膜切除术)的患者。主要结局是术后 30 天内和术后两年内死亡。使用多变量逻辑回归模型评估死亡的潜在危险因素。

结果

分析队列包括 1155 例患者,中位随访时间为 583 天。术后两年内死亡率为 16%。对于整个队列,血管麻醉师的护理与降低 30 天(优势比 0.22;95%置信区间 0.12-0.62)和中期死亡率(0.31;95%置信区间 0.18-0.55)独立相关。对于择期手术患者(n=851),血管麻醉降低了两年死亡率(优势比 0.29;95%置信区间 0.15-0.58;P=0.0004),但不降低 30 天死亡率(优势比 0.55;95%置信区间 0.15-1.95;P=0.35)。对于急诊患者,血管麻醉师的护理既不影响 30 天死亡率(优势比 0.33;95%置信区间 0.08-1.41;P=0.13),也不影响中期死亡率(优势比 0.45;95%置信区间 0.17-1.21;P=0.11)。

结论

麻醉专业降低了大血管手术后的早期和中期死亡率。如果前瞻性研究得到复制,这些结果表明血管外科服务将受益于专业的麻醉支持。

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