无溶剂超声化学法制备α-氨基膦酸酯的研究——以 1-己烷磺酸纳为催化剂。
Solvent-free sonochemical preparation of alpha-aminophosphonates catalyzed by 1-hexanesulphonic acid sodium salt.
机构信息
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India.
出版信息
Ultrason Sonochem. 2010 Jun;17(5):760-3. doi: 10.1016/j.ultsonch.2010.02.002. Epub 2010 Feb 8.
1-Hexanesulphonic acid sodium salt was found to be an efficient catalyst for the green synthesis of alpha-aminophosphonates by the coupling of aldehydes/ketone, an amine and triethyl phosphite under ultrasound irradiation at ambient temperature for appropriate time to furnish the desired product in good to excellent yield under solvent-free condition. This catalyst provides clean conversion; greater selectivity and easy workup make this protocol practical and economically attractive.
己烷磺酸纳被发现是一种高效的催化剂，用于在超声辐射下，于环境温度下，将醛/酮、胺和三乙基亚膦酸酯偶联，以合适的时间进行绿色合成α-氨基膦酸酯，在无溶剂条件下以良好到优秀的收率得到所需产物。该催化剂提供了清洁的转化；更高的选择性和易于后处理使该方案具有实际和经济吸引力。
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