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一种高效的铋盐催化合成α-氨基膦酸酯的路线。

A highly efficient bismuth salts-catalyzed route for the synthesis of α-aminophosphonates.

机构信息

Department of Chemistry, The University of Texas-Pan American, 1201 West University Drive, Edinburg, TX 78541, USA.

出版信息

Molecules. 2010 Nov 12;15(11):8205-13. doi: 10.3390/molecules15118205.

DOI:10.3390/molecules15118205
PMID:21076387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6259172/
Abstract

A convenient synthesis of different types of α-amino phosphonates via one-pot solvent-free three component reactions of aldehydes, amines and phosphites catalyzed by bismuth salts has been investigated. Bismuth triflate is found to be the most effective catalyst for this reaction.

摘要

研究了通过醛、胺和亚磷酸酯的一锅无溶剂三组分反应，在铋盐催化下方便地合成不同类型的α-氨基膦酸酯。发现三氟甲磺酸铋是该反应最有效的催化剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd27/6259172/86b0400a391b/molecules-15-08205-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd27/6259172/18971533e5ab/molecules-15-08205-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd27/6259172/86b0400a391b/molecules-15-08205-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd27/6259172/18971533e5ab/molecules-15-08205-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd27/6259172/86b0400a391b/molecules-15-08205-sch002.jpg

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