颈项透明层增厚且颈静脉囊扩张的胎儿其颈静脉和静脉导管血流速度改变。

Altered jugular vein and ductus venosus flow velocities in fetuses with increased nuchal translucency and distended jugular lymphatic sacs.

机构信息

Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Am J Obstet Gynecol. 2010 Jun;202(6):566.e1-8. doi: 10.1016/j.ajog.2010.01.054. Epub 2010 Mar 15.

DOI:10.1016/j.ajog.2010.01.054

PMID:20227670

Abstract

OBJECTIVE

We sought to assess blood flow in relation to jugular lymphatic distension in fetuses with increased and normal nuchal translucency (NT).

STUDY DESIGN

In all, 72 fetuses with normal NT and 71 fetuses with NT >95th percentile were evaluated. NT size, jugular lymphatic sacs (JLS), jugular vein and ductus venosus pulsatility index for veins (PIV), and intracardiac velocities were measured.

RESULTS

JLS were visualized in 22/72 fetuses with normal and in 55/71 fetuses with increased NT. Jugular vein and ductus venosus PIV was higher in fetuses with increased NT compared to normal NT (P < .01). Visibility of JLS was associated with a higher ductus venous PIV (P < .05), but not with a higher jugular vein PIV. Larger NT and larger JLS volumes were associated with higher jugular vein and ductus venosus PIV (P < .05).

CONCLUSION

This study shows a relation among increased NT, jugular lymphatic distension, and altered blood flow in jugular vein and ductus venosus.

摘要

目的

本研究旨在评估颈项透明层（NT）增厚和正常胎儿的颈静脉淋巴扩张与血流之间的关系。

研究设计

共评估了 72 例 NT 正常和 71 例 NT 大于第 95 百分位的胎儿。测量了 NT 大小、颈静脉淋巴囊（JLS）、颈静脉和静脉导管搏动指数（PIV）以及心内血流速度。

结果

在 NT 正常的 72 例胎儿中有 22 例和 NT 增加的 71 例胎儿中有 55 例可观察到 JLS。与 NT 正常的胎儿相比，NT 增加的胎儿颈静脉和静脉导管 PIV 更高（P <.01）。JLS 的可见性与更高的静脉导管 PIV 相关（P <.05），但与颈静脉 PIV 无关。更大的 NT 和更大的 JLS 体积与更高的颈静脉和静脉导管 PIV 相关（P <.05）。