Department of Psychology, University of Würzburg, Germany.
Clin Neurophysiol. 2010 Aug;121(8):1285-92. doi: 10.1016/j.clinph.2010.02.151. Epub 2010 Mar 15.
This study examined the sensitivity of event-related cortical potentials (ERPs) preceding and accompanying goal-directed hand movements to the variation of movement distance.
Participants performed linear hand movements to memorized target locations, which were arranged in distances between 10 and 31cm from the starting position of the hand. EPRs were analyzed time-locked to the imperative go signal as well as to the movement onset.
An increase in target distance was associated with an increase in amplitude of a negative component measured over sensorimotor areas that preceded movement onset (MP). Another negative deflection arising at similar scalp locations (N4) and following the MP decline was also highly distance dependent.
The data demonstrate distance specific brain activity accompanying accelerative and decelerative phases of motion during goal-directed hand movements.
The modulation of MP may to be related to the modulation of the initial force pulse, while N4 effects may reflect distance dependent changes in the magnitude of decelerative control.
本研究考察了与目标导向手运动相关的事件相关皮质电位(ERPs)在前导和伴随运动距离变化时的敏感性。
参与者执行线性手运动,以记忆目标位置,这些位置在手的起始位置到 10 到 31cm 之间排列。ERPs 与命令去信号以及运动开始时间锁定进行分析。
目标距离的增加与运动起始前(MP)测量的传感器运动区域的负分量的幅度增加相关。另一个在相似头皮位置(N4)产生的负偏转,在 MP 下降后也高度依赖于距离。
数据表明,在目标导向手运动过程中,伴随着加速和减速阶段的特定距离的大脑活动。
MP 的调制可能与初始力脉冲的调制有关,而 N4 效应可能反映了减速控制幅度的距离依赖性变化。