El Atat Rabih, Derouiche Amine, Guellouz Sabra, Gargah Tahar, Lakhoua Rachid, Chebil Mohamed
Department of Urology, Charles Nicolle Hospital, Tunis, Tunisia.
Saudi J Kidney Dis Transpl. 2010 Mar;21(2):251-7.
To report the surgical complications among our pediatric and adolescent renal transplants and to compare these results with other reported series in the literature. A total of 50 pediatric and adolescent renal transplants were included in this study. There were 30 boys and 20 girls with a mean age of 13 years (range 6 - 18 years). 70% of patients received their kidneys from living donors. Two patients underwent renal re-transplantation. Among the 52 transplantations, 17 surgical complications were encountered in 15(30%) patients. The incidence of urological and vascular complications was respectively 13.2% and 18.9%. These complications included vesico-ureteral reflux (9.4%), urinary leakage (3.8%), lymphocele (5.8%), peri-renal hematoma (1.9%), renal artery stenosis (3.7%), and thrombosis of the allograft (7.5%). The patients with vesico-ureteral reflux were treated by antibiotic prophylaxis. In four recipients, thrombosis of the allo-graft with subsequent graft loss occurred. The graft survival rate was 90% in 1 year, 77% in 5 years and 40% in 10 years follow-up. The patient survival rate was 94.4% in 1 year and 84% after 8 years follow-up. We conclude that surgical complications can be minimized if basic principles of careful transplant techniques are used. Prompt identification and treatment of any complication are critical for graft and patient survival.
报告我们儿科和青少年肾移植手术的并发症,并将这些结果与文献中其他报道的系列进行比较。本研究共纳入50例儿科和青少年肾移植病例。其中男孩30例,女孩20例,平均年龄13岁(范围6 - 18岁)。70%的患者接受活体供肾。2例患者接受了再次肾移植。在52次移植中,15例(30%)患者出现了17例手术并发症。泌尿系统和血管并发症的发生率分别为13.2%和18.9%。这些并发症包括膀胱输尿管反流(9.4%)、尿漏(3.8%)、淋巴囊肿(5.8%)、肾周血肿(1.9%)、肾动脉狭窄(3.7%)和移植肾血栓形成(7.5%)。膀胱输尿管反流患者采用抗生素预防治疗。4例受者发生移植肾血栓形成并随后移植肾丢失。随访1年时移植肾存活率为90%,5年时为77%,10年时为40%。随访1年时患者存活率为94.4%,8年时为84%。我们得出结论,如果采用仔细的移植技术基本原则,手术并发症可以降至最低。及时识别和治疗任何并发症对于移植肾和患者的存活至关重要。