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肾移植术后血管并发症的诊断与治疗策略:2304例肾移植单中心经验

Diagnostic and therapeutic strategies for vascular complications after renal transplantation: a single-center experience in 2,304 renal transplantations.

作者信息

Zhang Jiangwei, Xue Wujun, Tian Puxun, Zheng Jin, Ding Chenguang, Li Yang, Wang Ying, Ding Xiaoming

机构信息

Department of Renal Transplantation, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

出版信息

Front Transplant. 2023 May 11;2:1150331. doi: 10.3389/frtra.2023.1150331. eCollection 2023.

Abstract

Vascular complications after renal transplantation are one of the serious surgical complications, which can affect the transplantation outcome and even endanger life if not treated properly. We performed a retrospective analysis of the 2,304 renal transplantations procedures completed between the period of Jan., 2015 and Jan., 2022, which consisted of 1,658 male patients and 646 female patients. Among the above cases, there were 54 cases of vascular complications after renal transplantation, the incidence of vascular complications in our study was 2.34% (54/2,304), the most common vascular complication was transplanted renal artery stenosis (TRAS,  = 36), followed by external iliac artery dissection ( = 5), renal artery rupture ( = 4), renal vein thrombosis ( = 3), renal artery thrombosis ( = 2), renal artery dissection ( = 1), renal artery pseudoaneurysm ( = 1), and internal iliac artery pseudoaneurysm ( = 1), and renal artery kinking ( = 1). 40 patients were treated by percutaneous transluminal angioplasty (PTA), including 3 balloon catheter dilatation and 37 endovascular stentings, and 14 underwent open surgery. Eventually, 9 patients had graft nephrectomy, resulting in an overall treatment rate of 81.5%. Most vascular complications can be treated satisfactorily with PTA. However, the overall treatment of renal artery rupture, thrombosis, renal artery kinking, and other complications is poor, and the rate of transplanted renal loss is high.

摘要

肾移植术后血管并发症是严重的外科并发症之一,若处理不当可影响移植效果,甚至危及生命。我们对2015年1月至2022年1月期间完成的2304例肾移植手术进行了回顾性分析,其中男性患者1658例,女性患者646例。上述病例中,肾移植术后血管并发症54例,本研究中血管并发症发生率为2.34%(54/2304),最常见的血管并发症是移植肾动脉狭窄(TRAS,36例),其次是髂外动脉夹层(5例)、肾动脉破裂(4例)、肾静脉血栓形成(3例)、肾动脉血栓形成(2例)、肾动脉夹层(1例)、肾动脉假性动脉瘤(1例)、髂内动脉假性动脉瘤(1例)以及肾动脉扭曲(1例)。40例患者接受了经皮腔内血管成形术(PTA)治疗,其中3例行球囊导管扩张术,37例行血管内支架置入术,14例行开放手术。最终,9例患者接受了移植肾切除术,总体治疗有效率为81.5%。大多数血管并发症采用PTA治疗效果满意。然而,肾动脉破裂、血栓形成、肾动脉扭曲等并发症的总体治疗效果不佳,移植肾丢失率较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8625/11235313/d076bd04cce4/frtra-02-1150331-g001.jpg

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