Department of Neurosurgery, Taipei Hospital, Department of Health, Taipei, Taiwan, R.O.C.
J Chin Med Assoc. 2010 Mar;73(3):139-43. doi: 10.1016/S1726-4901(10)70028-9.
How to effectively use the finite resources of an intensive care unit (ICU) for neurosurgical patients is a critical decision-making process. Mortality prediction models are effective tools for allocating facilities. This study intended to distinguish the prediction power of the Acute Physiology and Chronic Health Evaluation II (APACHE II), the Simplified Acute Physiology Score II (SAPS II), and the Glasgow Coma Scale (GCS) for neurosurgical patients.
According to the definitions of the APACHE II, this study recorded both APACHE II and SAPS II scores of 154 neurosurgical patients in the ICU of a 600-bed general hospital. Linear regression models of GCS (GCS-mr) were constructed. The t test, receiver operating characteristic (ROC) curve and Wilcoxon signed rank test were used as the statistical evaluation methods.
There were 50 (32.5%) females and 104 (67.5%) males in this study. Among them, 108 patients survived and 46 patients died. The areas under the ROC curves (AUC) of SAPS II and APACHE II were 0.872 and 0.846, respectively. The AUC of GCS-mr was 0.866, and the R(2) was 0.389. The evaluation powers of SAPS II, GCS-mr and APACHE II were the same (p > 0.05). Patients with GCS <or= 5 or motor component of GCS (GCS-M) <or= 3 had a higher probability of mortality than patients with GCS > 5 or GCS-M > 3 (p < 0.01).
The predictive powers of SAPS II, APACHE II and GCS-mr were the same. The GCS-mr is more convenient for predicting mortality in neurosurgical patients. Both GCS <or= 5 and GCS-M <or= 3 are good indicators of mortality in these patients.
如何有效地利用重症监护病房(ICU)的有限资源对神经外科患者进行治疗是一个关键的决策过程。死亡率预测模型是分配设施的有效工具。本研究旨在区分急性生理学和慢性健康评估 II(APACHE II)、简化急性生理学评分 II(SAPS II)和格拉斯哥昏迷评分(GCS)对神经外科患者的预测能力。
根据 APACHE II 的定义,本研究记录了在一家 600 张床位的综合医院的 ICU 中 154 名神经外科患者的 APACHE II 和 SAPS II 评分。构建了 GCS(GCS-mr)的线性回归模型。使用 t 检验、接收者操作特征(ROC)曲线和 Wilcoxon 符号秩检验作为统计评估方法。
本研究中有 50 名(32.5%)女性和 104 名(67.5%)男性。其中 108 名患者存活,46 名患者死亡。SAPS II 和 APACHE II 的 ROC 曲线下面积(AUC)分别为 0.872 和 0.846。GCS-mr 的 AUC 为 0.866,R²为 0.389。SAPS II、GCS-mr 和 APACHE II 的评估能力相同(p>0.05)。GCS≤5 或 GCS-M≤3 的患者的死亡率高于 GCS>5 或 GCS-M>3 的患者(p<0.01)。
SAPS II、APACHE II 和 GCS-mr 的预测能力相同。GCS-mr 更便于预测神经外科患者的死亡率。GCS≤5 和 GCS-M≤3 都是这些患者死亡率的良好指标。