Department of Microbiology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Antimicrob Agents Chemother. 2010 May;54(5):2265-8. doi: 10.1128/AAC.01717-09. Epub 2010 Mar 15.
We determined the in vitro antimicrobial susceptibilities of 7,942 methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained from patients hospitalized in 48 Canadian hospitals from 1995 to 2008. Regional variations in susceptibilities were identified. The dissemination of community-associated strains in Canada appears to have contributed to increased susceptibility of MRSA to several non-beta-lactam antimicrobial agents in the past decade. Reduced susceptibility to glycopeptides was not identified.
我们测定了 1995 年至 2008 年期间,48 家加拿大医院住院患者中 7942 株耐甲氧西林金黄色葡萄球菌(MRSA)分离株的体外抗菌药敏性。发现了区域敏感性差异。在过去十年中,加拿大社区相关菌株的传播似乎导致 MRSA 对几种非β-内酰胺类抗菌药物的敏感性增加。未发现糖肽类药物的敏感性降低。