银屑病与心血管风险：数量即力量。
Psoriasis and cardiovascular risk: strength in numbers.
机构信息
Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
出版信息
J Invest Dermatol. 2010 Apr;130(4):919-22. doi: 10.1038/jid.2010.12.
Abstract
In this issue, Wakkee and colleagues report a self-described exploratory cohort study and conclude that psoriasis may not be an independent risk factor for ischemic heart disease (IHD) hospitalization and that there is only a slight and borderline increased risk of ischemic heart disease among psoriasis patients. This negative result should be interpreted in light of the study's limitations, the complex relationship among levels of psoriasis severity, patient age, and cardiovascular (CV) risk, and the context of the rapidly growing literature.
摘要
在本期中，Wakkee 及其同事报告了一项自描述的探索性队列研究，并得出结论，银屑病可能不是缺血性心脏病（IHD）住院的独立危险因素，并且银屑病患者的缺血性心脏病风险仅略有增加且处于边缘状态。考虑到研究的局限性、银屑病严重程度、患者年龄和心血管（CV）风险之间的复杂关系以及快速发展的文献背景，应该对这一阴性结果进行解释。
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