Department of Internal Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois 60153, USA.
J Hosp Med. 2010 Mar;5(3):141-7. doi: 10.1002/jhm.606.
To compare prevalence, clinical outcomes, and resource utilization between subjects with lower gastrointestinal bleeding (LGIB) and upper gastrointestinal bleeding (UGIB).
Using administrative data, patient surveys, and chart abstraction, comparisons between subjects admitted with LGIB and UGIB were made by employing bivariate and multivariate statistics.
A total of 367 subjects were identified, LGIB = 187 and UGIB = 180. Subjects with UGIB compared to LGIB had greater admission hemodynamic instability including tachycardia and orthostasis but clinical outcomes were similar. In multivariate analyses, no significant differences were observed for in-hospital mortality transfer to the intensive care unit (ICU) or 30-day readmission rate. Resource utilization was similar in UGIB and LGIB, including mean costs, length of stay, and number of endoscopic procedures.
Unlike prior studies, this direct comparison of LGIB to UGIB identified more similarities than differences with similar prevalence rates, clinical outcomes, and resource utilization, suggesting that the epidemiology of gastrointestinal bleeding may be changing.
比较下消化道出血（LGIB）和上消化道出血（UGIB）患者的患病率、临床结局和资源利用情况。
使用行政数据、患者调查和图表摘要，通过双变量和多变量统计方法对 LGIB 和 UGIB 入院患者进行比较。
共确定了 367 名患者，LGIB = 187 例，UGIB = 180 例。与 LGIB 相比，UGIB 患者入院时的血流动力学不稳定更明显，包括心动过速和直立性低血压，但临床结局相似。多变量分析显示，院内死亡率、转入重症监护病房（ICU）或 30 天再入院率无显著差异。UGIB 和 LGIB 的资源利用情况相似，包括平均费用、住院时间和内镜检查次数。
与先前的研究不同，本研究直接比较 LGIB 和 UGIB 发现，两者在患病率、临床结局和资源利用方面的相似之处多于不同之处，这表明胃肠道出血的流行病学可能正在发生变化。
