Department of Dermatology, Regensburg University Hospital, Regensburg, Germany.
J Eur Acad Dermatol Venereol. 2010 Nov;24(11):1261-9. doi: 10.1111/j.1468-3083.2010.03625.x.
Topical photodynamic therapy has shown to be effective for the treatment of several aspects of skin ageing. Multiple studies have demonstrated improvement of fine wrinkles, mottled hyperpigmentation, tactile roughness and sallowness. These results are supported by immunohistochemical analysis that revealed both upregulation of collagen production and increased epidermal proliferation. Neocollagenesis as an indirect dermal effect of photodynamic therapy is stimulated through cytokine induction. This article reviews the available literature for photodynamic rejuvenation while discussing cosmetic effects, light sources, adverse effects and the mechanism of action.
局部光动力疗法已被证明可有效治疗皮肤老化的多个方面。多项研究表明，它可改善细小皱纹、色素不均、触感粗糙和肤色发黄。免疫组织化学分析显示胶原生成增加和表皮增殖增加，为这些结果提供了支持。光动力疗法作为一种间接的真皮效应，通过细胞因子诱导刺激新胶原蛋白的形成。本文回顾了光动力焕肤的相关文献，同时讨论了其美容效果、光源、不良反应和作用机制。
