管化不仅仅是一个美丽的想法吗？
Is canalization more than just a beautiful idea?
机构信息
Department of Molecular Biology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
出版信息
Genome Biol. 2010;11(3):109. doi: 10.1186/gb-2010-11-3-109. Epub 2010 Mar 16.
Abstract
The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis.
摘要
热休克蛋白 90（Hsp90）目前被认为可以缓冲真核细胞免受先前存在的隐性遗传变异引起的干扰。一项新的研究表明，Hsp90 的缓冲功能可能是由于其抑制新形成的转座子介导的突变。
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