Int J Cardiol. 2011 Aug 4;150(3):e119-20. doi: 10.1016/j.ijcard.2010.02.069. Epub 2010 Mar 16.
Platelet donation by plateletpheresis is known to induce platelet and coagulation activation but there is no clear relationship between this acquired pre-thrombotic state and acute coronary syndrome in healthy donors. We report an acute myocardial infarction immediately following plateletpheresis in a 57-year-old donor with low atherosclerotic risk profile and no angiographic evidence of atherosclerotic disease strongly suggesting a causal relationship.
通过血小板分离术捐献血小板已知会引起血小板和凝血的激活,但这种获得性的血栓前状态与健康供体中的急性冠状动脉综合征之间没有明确的关系。我们报告了一例 57 岁供体在血小板分离术后立即发生急性心肌梗死的病例,该供体具有低动脉粥样硬化风险特征,且无动脉粥样硬化疾病的血管造影证据,强烈提示存在因果关系。