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[足月儿出生窒息:诊断、预后及神经保护]

[Birth asphyxia in term newborns: Diagnosis, prognosis, neuroprotection].

作者信息

Zupan Simunek V

机构信息

Service de réanimation néonatale, hôpital Antoine-Béclère, 157, rue de la Porte-de-Trivaux, 92141 Clamart cedex, France.

出版信息

Arch Pediatr. 2010 May;17(5):578-82. doi: 10.1016/j.arcped.2010.02.001. Epub 2010 Mar 16.

Abstract

Birth asphyxia occurs in 0.5% of term deliveries. Prognosis of newborns with birth asphyxia depends on clinical features of neonatal encephalopathy. The outcome of infants without encephalopathy is excellent. In contrast, neurological outcome of infants with encephalopathy is poor: 40 to 100% of neurodevelopmental disabilities according to the grade of encephalopathy. Prognosis can be more accurately assessed by EEG and MRI. Infants with encephalopathy following birth asphyxia must be referred as soon as possible in centers where neuroprotection by hypothermia is available.

摘要

足月儿分娩中出生窒息的发生率为0.5%。出生窒息新生儿的预后取决于新生儿脑病的临床特征。无脑病的婴儿预后良好。相比之下,患有脑病的婴儿神经学预后较差:根据脑病分级,40%至100%会出现神经发育障碍。脑电图和磁共振成像(MRI)能更准确地评估预后。出生窒息后患有脑病的婴儿必须尽快转诊至有低温神经保护治疗的中心。

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