Quinn G E, Dobson V, Barr C C, Davis B R, Flynn J T, Palmer E A, Robertson J, Trese M T
Division of Pediatric Ophthalmology, Children's Hospital of Philadelphia, PA 19104.
Ophthalmology. 1991 Jan;98(1):5-13. doi: 10.1016/s0161-6420(91)32343-1.
During the course of the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (CRYO-ROP), 98 infants (129 eyes) from the randomized segment of the trial developed total retinal detachment from retinopathy of prematurity (ROP) before the 1-year examination. The authors report as a case series the results of acuity card assessment of monocular grating acuity at 1 year in 53 infants (71 eyes) postvitrectomy and in 45 infants (58 eyes) who had retinal detachments but who did not undergo retinal reattachment surgery. The decision to undertake and the surgical technique used for a retinal reattachment procedure was not part of the randomized CRYO-ROP trial. Two eyes of one infant had pattern vision at the lowest measurable threshold after vitrectomy. None of the remaining eyes that had undergone vitrectomy and none of the eyes that did not undergo vitrectomy showed evidence of pattern vision. The relatively poor visual outcomes in this case series suggest that efforts are well-spent in attempting to prevent retinal detachment in ROP.
在早产儿视网膜病变冷冻治疗多中心试验（CRYO-ROP）过程中，该试验随机分组部分的98名婴儿（129只眼）在1年检查前因早产儿视网膜病变（ROP）发生了完全性视网膜脱离。作者将53名婴儿（71只眼）玻璃体切除术后1年单眼光栅视力的视力卡片评估结果以及45名婴儿（58只眼）发生视网膜脱离但未接受视网膜复位手术的结果作为病例系列进行报告。进行视网膜复位手术的决策及所采用的手术技术并非随机CRYO-ROP试验的一部分。一名婴儿的两只眼在玻璃体切除术后具有可测量的最低阈值的模式视力。其余接受玻璃体切除术的眼睛以及未接受玻璃体切除术的眼睛均未显示出模式视力的证据。该病例系列中相对较差的视觉结果表明，在预防ROP视网膜脱离方面付出努力是值得的。
