一种适用于测定升压物质的脊髓破坏大鼠制备模型。 - Suppr

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超能文献

A pithed rat preparation suitable for assaying pressor substances.

作者信息

SHIPLEY R E, TILDEN J H

出版信息

Proc Soc Exp Biol Med. 1947 Apr;64(4):453-5. doi: 10.3181/00379727-64-15828.

DOI:10.3181/00379727-64-15828

PMID:20239456

Abstract

摘要

相似文献

A pithed rat preparation suitable for assaying pressor substances.一种适用于测定升压物质的脊髓破坏大鼠制备模型。

Proc Soc Exp Biol Med. 1947 Apr;64(4):453-5. doi: 10.3181/00379727-64-15828.

Effects of moderate hypoxia, hypercapnia and acidosis on haemodynamic changes induced by endothelin-1 in the pithed rat.中度低氧、高碳酸血症和酸中毒对去脑大鼠中内皮素-1诱导的血流动力学变化的影响。

Br J Pharmacol. 1989 Nov;98(3):1055-65. doi: 10.1111/j.1476-5381.1989.tb14638.x.

Effects of nifedipine, BAY K 8644, and pertussis toxin on pressor response to sarafotoxin-b in pithed rats.硝苯地平、BAY K 8644和百日咳毒素对脊髓横断大鼠对萨拉毒素-b升压反应的影响。

J Cardiovasc Pharmacol. 1990 Sep;16(3):495-500. doi: 10.1097/00005344-199009000-00021.

A unique pressor response to isoprenaline in the pithed rat during triiodo-L-thyronine(T3)-induced hyperthyroidism.在三碘-L-甲状腺原氨酸（T3）诱导的甲状腺功能亢进期间，去大脑大鼠对异丙肾上腺素的独特升压反应。

Naunyn Schmiedebergs Arch Pharmacol. 1986 Oct;334(2):138-44. doi: 10.1007/BF00505813.

Investigation of the subtype of alpha 2-adrenoceptor mediating pressor responses in the pithed rat.去大脑大鼠中介导升压反应的α2-肾上腺素能受体亚型的研究。

Eur J Pharmacol. 1996 Dec 27;318(1):81-7. doi: 10.1016/s0014-2999(96)00780-7.

Yohimbine antagonises α1A- and α1D-adrenoceptor mediated components in addition to the α2A-adrenoceptor component to pressor responses in the pithed rat.育亨宾拮抗α1A-和α1D-肾上腺素受体介导的成分，除了α2A-肾上腺素受体成分，以加压反应在被切断脑的大鼠。

Eur J Pharmacol. 2012 Mar 15;679(1-3):90-4. doi: 10.1016/j.ejphar.2012.01.001. Epub 2012 Jan 21.

Acute hyperglycemia and hyperinsulinemia enhance adrenergic vasoconstriction and decrease calcitonin gene-related peptide-containing nerve-mediated vasodilation in pithed rats.急性高血糖和高胰岛素血症可增强去甲肾上腺素能血管收缩，并减少去脑大鼠中含降钙素基因相关肽的神经介导的血管舒张。

Hypertens Res. 2008 May;31(5):1033-44. doi: 10.1291/hypres.31.1033.

The pressor effects of paraoxon in the pithed rat.对氧磷对脊髓麻醉大鼠的升压作用。

Br J Pharmacol. 1982 Oct;77(2):233-8. doi: 10.1111/j.1476-5381.1982.tb09290.x.

Effects of insulin on vascular responses to spinal cord stimulation and vasoactive agents in pithed rats.胰岛素对脊髓损伤大鼠血管对脊髓刺激和血管活性药物反应的影响。

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KT3-671, an angiotensin AT1 receptor antagonist, attenuates vascular but not cardiac responses to sympathetic nerve stimulation in pithed rats.血管紧张素AT1受体拮抗剂KT3-671可减弱去大脑大鼠对交感神经刺激的血管反应，但不影响心脏反应。

J Cardiovasc Pharmacol. 2001 Apr;37(4):427-36. doi: 10.1097/00005344-200104000-00010.

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Pharmacological analysis of the increases in heart rate and diastolic blood pressure produced by (S)-isometheptene and (R)-isometheptene in pithed rats.（S）-异美汀和（R）-异美汀对去脑大鼠心率及舒张压升高作用的药理学分析。

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Olcegepant blocks neurogenic and non-neurogenic CGRPergic vasodepressor responses and facilitates noradrenergic vasopressor responses in pithed rats.在脊髓横断大鼠中，olcegepant可阻断神经源性和非神经源性降钙素基因相关肽能血管舒张反应，并促进去甲肾上腺素能血管收缩反应。

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The role of dopamine D2, but not D3 or D4, receptor subtypes, in quinpirole-induced inhibition of the cardioaccelerator sympathetic outflow in pithed rats.多巴胺D2受体亚型而非D3或D4受体亚型在喹吡罗诱导的脊髓横断大鼠心脏交感神经传出冲动抑制中的作用。

Br J Pharmacol. 2013 Nov;170(5):1102-11. doi: 10.1111/bph.12358.

Predominant role of the dopamine D3 receptor subtype for mediating the quinpirole-induced inhibition of the vasopressor sympathetic outflow in pithed rats.多巴胺 D3 受体亚型在介导喹吡罗引起的电刺激大鼠主动脉弓压力感受器引起的加压交感神经传出抑制中的主要作用。

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Role of alpha adrenoceptors and nitric oxide on cardiovascular responses in acute and chronic hypertension.α肾上腺素能受体和一氧化氮在急、慢性高血压心血管反应中的作用。

J Physiol Biochem. 2011 Sep;67(3):427-35. doi: 10.1007/s13105-011-0093-3. Epub 2011 Apr 15.

Urethane, but not pentobarbitone, attenuates presynaptic receptor function in rats: a contribution to the choice of anaesthetic.氨基甲酸乙酯而非戊巴比妥钠可减弱大鼠突触前受体功能：对麻醉选择的贡献。

Br J Pharmacol. 2009 Aug;157(8):1474-82. doi: 10.1111/j.1476-5381.2009.00315.x.

Pharmacological characterization of ergotamine-induced inhibition of the cardioaccelerator sympathetic outflow in pithed rats.麦角胺对脊髓麻醉大鼠心脏加速交感神经传出抑制作用的药理学特性研究。

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Further characterization of the 5-HT1 receptors mediating cardiac sympatho-inhibition in pithed rats: pharmacological correlation with the 5-HT1B and 5-HT1D subtypes.在脊髓横断大鼠中介导心脏交感神经抑制的5-羟色胺1型受体的进一步特性研究：与5-羟色胺1B和5-羟色胺1D亚型的药理学相关性

Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):220-7. doi: 10.1007/s00210-003-0842-0. Epub 2003 Dec 12.

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