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[脊髓麻醉中的风险与血流动力学不稳定]

[Risk and hemodynamic instability in spinal anesthesia].

作者信息

Hemmingsen C, Følsgaard S L, Frey-Larsen S, Jacobsen E

机构信息

Anaestesiafdeling AN og medicinsk afdeling B, Rigshospitalet, København.

出版信息

Ugeskr Laeger. 1991 Apr 8;153(15):1052-5.

PMID:2024329
Abstract

We investigated 131 consecutive patients who were submitted to orthopaedic surgical interventions under spinal anaesthesia during a period of 12 months. Prior to operation, all of the patients were classified according to the Boston Cardiac Risk Index. Immediately before operation, approximately 500 ml sodium chloride solution was infused. Patients were registered as haemodynamically unstable when a peroperative fall in the mean arterial pressure of more than 30% occurred or when the systolic blood pressure fell to less than 80 mmHg. In 40 patients, haemodynamically unstable conditions developed peroperatively while 91 were haemodynamically stable. In Boston group III, 67% of the patients were haemodynamically unstable peroperatively which was significantly more than in the Boston group I (25%) and the Boston group II (32%) (p less than 0.005). The postoperative mortality was significantly higher (13%) among the total number of peroperatively haemodynamically unstable patients than among the peroperatively stable patients (3%) (p less than 0.05). In Boston group III, the postoperative mortality was 42% as compared with 1% and 7% in the Boston groups I and II, respectively (p less than 0.05). It is concluded that the risk of fall in blood pressure during spinal anaesthesia may be predicted by the Boston Cardiac Risk Index and that patients who develop haemodynamic instability during spinal anaesthesia have an increased risk of developing complications. These patients should be offered maximal postoperative observation and care.

摘要

我们调查了12个月期间131例连续接受脊髓麻醉下骨科手术干预的患者。术前,所有患者均根据波士顿心脏风险指数进行分类。手术即将开始前,输注约500ml氯化钠溶液。若术中平均动脉压下降超过30%或收缩压降至低于80mmHg,则将患者登记为血流动力学不稳定。40例患者术中出现血流动力学不稳定情况,91例血流动力学稳定。在波士顿III组中,67%的患者术中血流动力学不稳定,显著高于波士顿I组(25%)和波士顿II组(32%)(p<0.005)。术中血流动力学不稳定的患者总数术后死亡率(13%)显著高于术中稳定的患者(3%)(p<0.05)。在波士顿III组中,术后死亡率为42%,而波士顿I组和II组分别为1%和7%(p<0.05)。结论是,波士顿心脏风险指数可预测脊髓麻醉期间血压下降的风险,且脊髓麻醉期间出现血流动力学不稳定的患者发生并发症的风险增加。应给予这些患者最大程度的术后观察和护理。

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