等长运动对冠脉循环中儿茶酚胺的影响。

Effect of isometric exercise on catecholamines in the coronary circulation.

作者信息

Robson R H, Fluck D C

出版信息

Eur J Appl Physiol Occup Physiol. 1977 Dec 22;37(4):289-95. doi: 10.1007/BF00430958.

PMID:202452

Abstract

Arterial and coronary sinus blood levels of catecholamines, adenosine 3', 5'-cyclic monophosphate (c-AMP) and lactate were measured during isometric exercise in fourteen patients. In no patient did lactate production occur. Mean resting total catecholamine levels both arterial (0.53 +/- 0.07 ng/ml; 2.94 +/- 0.38 nmol/l) and coronary sinus (0.4 +/- 0.08 ng/ml; 2.22 +/- 0.44 nmol/l), did not change significantly on exercise. Coronary sinus c-AMP levels fell on exercise from 11.5 +/- 0.8 nmol/l (resting) to 9.9 +/- 0.8 nmol/l (exercise) (P less than 0.01) with an arterial-coronary sinus difference of 1.2 nmol/l (P less than 0.01) on exercise. Our findings suggest that isometric exercise does not normally result in excessive cardiac symphathetic activity.

摘要

在14名患者进行等长运动期间，测量了动脉血和冠状窦血中儿茶酚胺、3',5'-环磷酸腺苷（c-AMP）和乳酸的水平。所有患者均未出现乳酸生成。静息时动脉血中儿茶酚胺平均总水平（0.53±0.07 ng/ml；2.94±0.38 nmol/l）和冠状窦血中儿茶酚胺平均总水平（0.4±0.08 ng/ml；2.22±0.44 nmol/l）在运动时均无显著变化。运动时冠状窦c-AMP水平从静息时的11.5±0.8 nmol/l降至9.9±0.8 nmol/l（P<0.01），运动时动脉血与冠状窦血的差值为1.2 nmol/l（P<0.01）。我们的研究结果表明，等长运动通常不会导致过度的心脏交感神经活动。