Arbus G S, Rochon J, Thompson D
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Pediatr Nephrol. 1991 Jan;5(1):152-7. doi: 10.1007/BF00852874.
Evidence from multicenter registries has suggested that cadaveric renal graft survival is poorer when either the recipient or the donor is very young. We therefore analyzed our results from a single pediatric center. There was a significant correlation between greater recipient age and improved cadaveric graft (P = 0.002) and patient (P = 0.0009) survival. The age of the donor also appeared important, particularly in very young children, but became less so as donor age rose. Forty-four percent of recipients under 3 years old who received cadaveric kidneys from donors less than 4 years old lost their grafts as a result of renal thrombosis, ischemia, or technical problems, compared with only 3% of recipients over 9 years of age, whose grafts came from donors who were also over 9 years. The 1-year first cadaveric graft survival rates for these two age groups were 33% and 82% respectively. Our experience confirms the poor findings reported in very young recipients and with very young donors.
多中心登记处的数据表明，当受者或供者非常年轻时，尸体肾移植的存活率较低。因此，我们分析了来自单一儿科中心的结果。受者年龄越大与尸体肾移植存活率提高（P = 0.002）及患者存活率提高（P = 0.0009）之间存在显著相关性。供者年龄似乎也很重要，尤其是在非常年幼的儿童中，但随着供者年龄的增加，其重要性降低。接受来自4岁以下供者尸体肾的3岁以下受者中，44%因肾血栓形成、缺血或技术问题失去了移植肾，而移植肾来自9岁以上供者的9岁以上受者中，这一比例仅为3%。这两个年龄组的首次尸体肾移植1年存活率分别为33%和82%。我们的经验证实了在非常年轻的受者和非常年轻的供者中所报道的不良结果。
