两种长爪沙鼠（Meriones unguiculatus）种群对钩端螺旋体的易感性差异
Differential susceptibility of two stocks of Mongolian gerbils (Meriones unguiculatus) to Leptospira.
作者信息
Yukawa M
机构信息
Laboratory of Biomedical Science, Nihon University, Veterinary School, Japan.
出版信息
J Exp Anim Sci. 1991;34(1):1-5.
PMID:2025654
Abstract
Mongolian gerbils (Meriones unguiculatus) of Tumble Blook (TUM) and Japan Medical Science (JMS) stocks were compared with regard to susceptibility to Leptospira interrogans serovar copenhageni. The TUM gerbil died 6 to 9 d after intraperitoneal inoculation with 10 organisms, showing jaundice and systemic hemorrhage. However, 25% of the JMS gerbils survived infection with 10(3) or 10(4) organisms and there was no fatal case after infection with 10(2) organisms.
摘要
比较了Tumble Blook（TUM）品系和日本医学科学（JMS）品系的蒙古沙鼠（长爪沙鼠）对问号钩端螺旋体哥本哈根血清型的易感性。TUM品系的沙鼠经腹腔接种10个菌体后6至9天死亡，表现出黄疸和全身出血。然而，25%的JMS品系沙鼠在感染10³或10⁴个菌体后存活下来，感染10²个菌体后没有出现死亡病例。
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