Acute lymphoblastic leukemia with t(4;11) translocation after osteogenic sarcoma.
作者信息
Kapelushnik J, Dubé I, Wilson P, Greenberg M
机构信息
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
出版信息
Cancer. 1991 Jun 1;67(11):2887-9. doi: 10.1002/1097-0142(19910601)67:11<2887::aid-cncr2820671130>3.0.co;2-f.
Abstract
The authors report a case of acute lymphoblastic leukemia (ALL) with t(4;11) (q21;q23) occurring 9 months after treatment of osteogenic sarcoma. Cell surface marker and molecular analyses suggest early B lineage involvement. This is the first report, to the knowledge of the authors, of t(4;11) ALL arising after an osteogenic sarcoma. The observations of the authors support the possibility of a causal relationship between exposure to carcinogens and the occurrence of leukemia with t(4;11).
摘要
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