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成年猴子双侧中央凹损伤后中央凹V1神经元视觉反应的恢复

Recovery of visual responses in foveal V1 neurons following bilateral foveal lesions in adult monkey.

作者信息

Heinen S J, Skavenski A A

机构信息

Psychology Department, Northeastern University, Boston, MA 02115.

出版信息

Exp Brain Res. 1991;83(3):670-4. doi: 10.1007/BF00229845.

DOI:10.1007/BF00229845
PMID:2026207
Abstract

Cells in the foveal representation of V1 cortex of adult primates became visually responsive after normal sensory input was removed. Immediately after fovea were lesioned bilaterally, a region was found where no cells' activity could be modulated by visual stimulation. Recordings made in that deafferented zone at greater than 2.5 months after lesions revealed that activity of over half of the cells could be modulated by visual stimuli presented to intact peripheral retina. Although response characteristics made cells with recovered driving quite unlike normal cells, the result suggests a level of visual cortical reorganization previously observed only in immature animals.

摘要

成年灵长类动物V1皮层中央凹表征区域的细胞在正常感觉输入被移除后仍对视觉产生反应。在双侧中央凹受损后,立即发现一个区域,其中细胞活动无法被视觉刺激调节。在损伤后超过2.5个月于该去传入区域进行的记录显示,超过一半的细胞活动可被呈现给完整周边视网膜的视觉刺激调节。尽管反应特征使恢复驱动的细胞与正常细胞截然不同,但该结果表明了一种以前仅在未成熟动物中观察到的视觉皮层重组水平。

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