Ström K, Boe J
Division of Chest Medicine, Central Hospital, Karlskrona, Sweden.
Eur Respir J. 1991 Jan;4(1):50-8.
On January 1, 1987, 560 patients (267 male) were registered as using long-term domiciliary oxygen therapy (LTO) in Sweden. The duration of LTO before this date varied between 10 days and 11 yrs. During a two-year follow-up 12 patients had their LTO withdrawn because they were no longer hypoxic. In 139 patients the arterial oxygen tension (PaO2) on breathing air was registered three times. In seventeen (12%) of these patients the PaO2 exceeded 7.5 kPa on all three control occasions. The two year actuarial survival in all patients was 57%. The two year actuarial survival was 77% in patients with kyphoscoliosis, 56% in patients with sequelae of tuberculosis, 54% in patients with chronic obstructive pulmonary disease (COPD) and 39% in patients with fibrosis. In COPD patients survival was predicted by age, sex, current smoking habits, arterial carbon dioxide tension (PacO2) when breathing oxygen and oral steroid medication. A poor Zubrod performance score was associated with a high mortality rate in all patient groups.
1987年1月1日,瑞典有560名患者(267名男性)登记使用长期家庭氧疗(LTO)。在此日期之前,LTO的持续时间在10天至11年之间。在为期两年的随访中,有12名患者因不再缺氧而停止LTO治疗。139名患者的呼吸空气时的动脉血氧分压(PaO2)被记录了三次。其中17名(12%)患者在所有三次对照检查中PaO2均超过7.5kPa。所有患者的两年精算生存率为57%。脊柱侧凸患者的两年精算生存率为77%,肺结核后遗症患者为56%,慢性阻塞性肺疾病(COPD)患者为54%,纤维化患者为39%。在COPD患者中,生存率可通过年龄、性别、当前吸烟习惯、吸氧时的动脉血二氧化碳分压(PacO2)和口服类固醇药物来预测。在所有患者组中,较差的佐布罗德表现评分与高死亡率相关。