Warren S E, Grossman W
Charles A. Dana Research Institute, Beth Israel Hospital, Boston, Massachusetts.
Herz. 1991 Feb;16(1):33-45.
The therapeutic approaches affecting diastolic ventricular function are conditional on underlying physiology, especially as it relates to calcium cycling, early relaxation and rapid filling abnormalities, atrial function, hemodynamics, the presence of hypertrophy, and neurohormonal milieu. A wide variety of treatment considerations are discussed, with particular attention to the management of cardiomyopathy characterized by pure or predominant diastolic failure (Table 1).
影响舒张期心室功能的治疗方法取决于潜在的生理机制,尤其是与钙循环、早期舒张和快速充盈异常、心房功能、血流动力学、肥厚的存在以及神经激素环境有关的生理机制。本文讨论了多种治疗考量因素,特别关注以单纯或主要舒张功能衰竭为特征的心肌病的管理(表1)。