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[颈部淋巴结。采用梯度回波技术的磁共振诊断]

[Lymph nodes of the neck. Diagnosis using magnetic resonance with gradient-echo technique].

作者信息

Andreula C F, Farchi G, Pavone V, Racanelli A, Carella A

机构信息

Neuroradiologia, Università, Bari.

出版信息

Radiol Med. 1991 Apr;81(4):417-21.

PMID:2028032
Abstract

As for the pathologic conditions of neck lymph nodes, the clinician needs to know if the involved node is reactive, phlogistic, or neoplastic in nature. If accurate tumor staging is required, imaging techniques play a fundamental role. Our study was aimed at assessing the actual role of MR imaging in the evaluation of neck lymph node involvement. The study was performed using an MR Max Plus by General Electrics operating with an 0.5 T superconductive magnet. We employed gradient-echo (GE) pulse sequences with TR 500, TE 15 ms and 90 degrees flip angle for T1-weighted images, and with TR 500, TE 30 ms and 25-30 degrees flip angles for T2-weighted images; for Pd-T2-weighted images, TR was 520, TE 30 ms, and flip angles were 40-45 degrees. The results were correlated with histopathologic findings obtained at biopsy. The advantages of GE sequences were: 1) whole neck imaging--thus saving time, and reducing radiation dose and contrast media; 2) optimal anatomical and topographic evaluation of the lesion; 3) imaging of the longitudinal diameter of the node; 4) higher sensitivity for lymph node tissue modifications; 5) imaging of necrosis, hemorrhage, and/or fibrosis. GE sequences were especially useful for accurate tumor staging, in the follow-up, and to verify response to therapy. However, even though MR imaging has proven to have high sensitivity, its specificity was similar to that of contrast-enhanced CT. Further studies with the use of paramagnetic contrast media are needed to solve these problems.

摘要

至于颈部淋巴结的病理状况,临床医生需要了解受累淋巴结本质上是反应性、炎性还是肿瘤性的。如果需要准确的肿瘤分期,成像技术起着至关重要的作用。我们的研究旨在评估磁共振成像(MR成像)在评估颈部淋巴结受累情况中的实际作用。该研究使用的是通用电气公司的MR Max Plus,配备0.5T超导磁体。我们采用梯度回波(GE)脉冲序列,T1加权图像的TR为500、TE为15ms、翻转角为90度,T2加权图像的TR为500、TE为30ms、翻转角为25 - 30度;质子密度加权T2加权图像的TR为520、TE为30ms、翻转角为40 - 45度。将结果与活检时获得的组织病理学结果进行关联。GE序列的优点包括:1)全颈部成像——从而节省时间、减少辐射剂量和造影剂用量;2)对病变进行最佳的解剖和地形学评估;3)对淋巴结的纵向直径进行成像;4)对淋巴结组织改变具有更高的敏感性;5)对坏死、出血和/或纤维化进行成像。GE序列在准确的肿瘤分期、随访以及验证治疗反应方面特别有用。然而,尽管MR成像已被证明具有高敏感性,但其特异性与增强CT相似。需要进一步使用顺磁性造影剂进行研究以解决这些问题。

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