Contrast-enhanced gradient-echo MR imaging of the head and neck: experimental and clinical assessment.

To clarify the enhancement pattern of gradient-echo (GE) MR imaging, phantom experiments and 24 clinical examinations of the head and neck region were performed. Both long repetition time (TR) GE and short TR GE pulse sequences demonstrated an enhancement pattern similar to T1-weighted spin-echo imaging in phantom experiments, although the signal intensity of water and gadopentetate dimeglumine (Gd) solution was higher and the signal intensity of fat was lower with the GE technique. In clinical examinations, contrast-enhanced GE imaging was beneficial for tumors within fatty tissue, and for tumors with calcification or other magnetic susceptibility difference.