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成人先天性梅毒脑脊髓炎表现

[Congenital syphilitic meningomyelitis manifested in the adult].

作者信息

Lanoë Y, Amarenco G, Deleau B, Aymard A, Goudal H

机构信息

Service de Neurologie, Centre Hospitalier Robert Ballanger, Aulnay-sous-Bois.

出版信息

Rev Neurol (Paris). 1991;147(2):167-70.

PMID:2028154
Abstract

We report a case of neurosyphilis of the spinal cord in a 38-year-old-man presenting with urinary incontinence and Argyll-Robertson sign. Anamnesis revealed the congenital origin of the disease. Urodynamics findings were consistent with a conus medullaris involvement and CSF study revealed a specific lymphocytic meningitis. A specific spinal arteritis was found by angiography. A quarterly 15 to 20 days course of intravenous penicillin was then instituted during 2 years. A specific treatment of urinary symptoms resulted in complete disappearance of sphincter dyssynergia. Antibiotic therapy was followed by clinical improvement and regression of most of the CSF abnormalities.

摘要

我们报告了一例38岁男性脊髓型神经梅毒病例,该患者表现为尿失禁和阿-罗瞳孔。既往史显示该病为先天性起源。尿动力学检查结果与圆锥受累相符,脑脊液检查显示为特异性淋巴细胞性脑膜炎。血管造影发现特异性脊髓动脉炎。随后在2年期间每季度进行15至20天的静脉青霉素治疗。针对尿路症状的特异性治疗使括约肌协同失调完全消失。抗生素治疗后临床症状改善,大多数脑脊液异常情况消退。

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