Rigaud A S
Service de psychiatrie adulte du Pr. André Féline, hôpital de Bicêtre, Le Kremlin-Bicêtre.
Rev Prat. 1991 Mar 1;41(7):601-5.
Depressive symptoms are frequent during schizophrenia. Depression occurs in the course of a schizo affective psychose or in the course of a schizophrenia (either with acute psychotic symptoms, either without acute psychotic symptoms). Differentiating depression from negative symptoms of schizophrenia or from antipsychotic drug induced side effects can be difficult. The question to know whether depression is intrinsic to the disease process itself whether it is secondary to the schizophrenic process is still a matter of inquiry. Efficacy of antidepressive drugs during depression in schizophrenia remains a matter of controversy. Depression increases the risk for pejorative evolution and for suicide in schizophrenia.
抑郁症状在精神分裂症患者中很常见。抑郁症可发生于分裂情感性精神病过程中，或精神分裂症过程中（伴有急性精神病性症状或无急性精神病性症状）。区分抑郁症与精神分裂症的阴性症状或抗精神病药物引起的副作用可能很困难。抑郁症是疾病过程本身所固有的，还是精神分裂症过程继发的，这一问题仍有待探讨。抗抑郁药物对精神分裂症伴发抑郁症的疗效仍存在争议。抑郁症会增加精神分裂症病情恶化和自杀的风险。
