van Iddekinge B, Gobetz L, Seaward P G, Hofmeyr G J
Department of Obstetrics and Gynaecology, Johannesburg Hospital, RSA.
S Afr Med J. 1991 May 18;79(10):620-2.
Despite the widespread use of beta-sympathomimetic agents for preterm labour there appears to be a limited appreciation of the need for cardiovascular monitoring in the mother. Four patients in whom pulmonary oedema developed during tocolysis with hexoprenaline are described and the aetiological factors and pathogenesis of this potentially lethal complication discussed. Guidelines for the safe use of hexoprenaline in preterm labour are suggested.
尽管β-拟交感神经药在早产治疗中广泛应用,但对于母亲进行心血管监测的必要性似乎认识不足。本文描述了4例在使用海索那林抑制宫缩过程中发生肺水肿的患者,并讨论了这种潜在致命并发症的病因及发病机制。同时提出了在早产治疗中安全使用海索那林的指南。