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视网膜电图振荡电位的产后发育。II. 明视觉特征。

The postnatal development of the oscillatory potentials of the electroretinogram. II. Photopic characteristics.

作者信息

el Azazi M, Wachtmeister L

机构信息

Department of Ophthalmology, Karolinska Institute/Huddinge University Hospital, Sweden.

出版信息

Acta Ophthalmol (Copenh). 1991 Feb;69(1):6-10. doi: 10.1111/j.1755-3768.1991.tb01983.x.

DOI:10.1111/j.1755-3768.1991.tb01983.x
PMID:2028769
Abstract

The postnatal development of the oscillatory potentials (OPs) of the rat's electroretinogram (ERG) was studied during more extreme photopic conditions. The appearance of the OPs was further delayed, by 1 to 3 days, compared to previously studied less photopic conditions. A rapid phase of development of the total OP activity occurred at the age of 15 days, which coincided with the physiological opening of the eye-lids. During maturation the first two OPs were enhanced while the later OPs were attenuated. The total OP activity culminated at the age of 30 days. These results strongly indicate that the rapid neuronal adaptive system appears and develops later than the slow photochemical one. Secondly, the fast phase of maturation of the neuronal adaptive process, as reflected in the OPs, seems to be dependent on environmental light. Thirdly, the findings support previous indications that two different systems seem to be responsible for the OPs in the rat and thus the earlier OPs to have different origins from those of the later ones.

摘要

在更为极端的明视觉条件下,对大鼠视网膜电图(ERG)振荡电位(OPs)的产后发育进行了研究。与之前在光照较弱条件下的研究相比,OPs的出现进一步延迟了1至3天。总OP活动在15日龄时出现快速发育阶段,这与眼睑的生理性睁开相吻合。在成熟过程中,前两个OP增强,而后期的OP减弱。总OP活动在30日龄时达到顶峰。这些结果有力地表明,快速神经元自适应系统的出现和发育比缓慢的光化学系统要晚。其次,如OPs所反映的,神经元自适应过程的快速成熟阶段似乎依赖于环境光。第三,这些发现支持了之前的观点,即大鼠的OPs似乎由两个不同的系统负责,因此早期的OPs与后期的OPs起源不同。

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