Buck G M, Michalek A M, Kramer A A, Batt R E
Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, SUNY, Buffalo 14214.
Am J Epidemiol. 1991 May 1;133(9):900-6. doi: 10.1093/oxfordjournals.aje.a115969.
The purpose of this study was to assess whether labor and delivery events were risk factors for sudden infant death syndrome (SIDS). A nested case-control design was used. From the 1974 cohort of live births for Upstate New York (exclusive of New York City), resident mothers (n = 132,948), SIDS cases, and living controls were selected. Data were abstracted from hospital delivery and vital records for 148 autopsied cases and 355 frequency-matched controls. With the use of unconditional logistic regression, no increase in SIDS risk was observed for artificial rupture of membranes, medication use during labor, induction/augmentation of labor, or anesthesia for delivery. An increased risk of SIDS was observed for labor 16 hours or more (odds ratio (OR) = 2.6, 95% confidence interval (CI) 1.1-6.5) and vaginal breech delivery (OR = 7.2, 95% CI 0.7-72.2). Significant inverse trends were observed for Apgar scores and risk of SIDS.
本研究的目的是评估分娩事件是否为婴儿猝死综合征（SIDS）的危险因素。采用巢式病例对照设计。从纽约州北部（不包括纽约市）1974年出生队列中的常住母亲（n = 132,948）中选取SIDS病例和存活对照。从148例尸检病例和355例频率匹配对照的医院分娩记录和生命记录中提取数据。使用无条件逻辑回归分析，未观察到人工破膜、分娩期间用药、引产/加强宫缩或分娩麻醉会增加SIDS风险。分娩持续16小时或更长时间（优势比（OR）= 2.6，95%置信区间（CI）1.1 - 6.5）和阴道臀位分娩（OR = 7.2，95% CI 0.7 - 72.2）时，SIDS风险增加。观察到阿氏评分与SIDS风险呈显著负相关趋势。
