Vitiello R, Benson L, Musewe N, Freedom R
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Br Heart J. 1991 Apr;65(4):211-2. doi: 10.1136/hrt.65.4.211.
Catheter occlusion of the persistent ductus arteriosus recently became clinically available with a Rashkind (USCI Bellerica, Massachusetts, USA) umbrella occluder system. A few patients, however, had residual left to right shunting after the procedure. The impact of soaking the foam of the device in a thrombin solution to enhance clotting and of using a device with a diameter of 12 or 17 mm was assessed in 117 consecutive patients undergoing catheter closure. The frequency of residual shunting detected by colour flow Doppler 24 hours after the procedure was the same whether or not thrombin was used.
最近,采用美国马萨诸塞州贝勒里卡市USCI公司的拉什金德伞封堵器系统,经导管闭合动脉导管未闭在临床上已成为可行的方法。然而,少数患者在术后仍存在左向右分流。在117例接受导管闭合术的连续患者中,评估了将装置的泡沫浸泡在凝血酶溶液中以增强凝血的效果以及使用直径为12或17mm的装置的影响。术后24小时通过彩色多普勒血流显像检测到的残余分流频率,无论是否使用凝血酶均相同。