Department of Radiology, The University of Chicago Medical Center, Chicago, IL 60637, USA.
Cancer Imaging. 2010 Mar 18;10(1):114-6. doi: 10.1102/1470-7330.2010.0015.
The authors report the fluorodeoxyglucose (FDG)-positron emission tomography(PET)/computed tomography (CT) findings of a rare case of growth hormone-secreting pituitary carcinoma with multiple metastatic lesions to the skeleton. A 31-year-old male had presented with acromegaly and had received transsphenoidal resection of a pituitary tumor and adjuvant radiotherapy. However, the tumor recurred with local invasions and the patient underwent more resections and adjuvant chemotherapy. Several months later, the patient developed rising levels of insulin-like growth factor 1 and whole-body FDG-PET/CT scanning revealed multiple hypermetabolic lesions throughout the skeleton compatible with metastasis.
作者报告了一例罕见的生长激素分泌性垂体癌伴多处骨骼转移的氟脱氧葡萄糖(FDG)-正电子发射断层扫描(PET)/计算机断层扫描(CT)结果。一名 31 岁男性因肢端肥大症就诊,曾接受经蝶窦垂体瘤切除术和辅助放疗。然而,肿瘤复发并伴有局部侵犯,患者接受了更多的切除术和辅助化疗。几个月后,患者出现胰岛素样生长因子 1 水平升高,全身 FDG-PET/CT 扫描显示全身多处骨骼高代谢病变符合转移。