极低频重复经颅磁刺激可调节对侧半球的体感诱发电位。

Very low-frequency rTMS modulates SEPs over the contralateral hemisphere.

作者信息

Uguisu Haruo, Urushihara Ryo, Hosono Yuki, Asanuma Kotaro, Shimazu Hideki, Murase Nagako, Kaji Ryuji

机构信息

Department of Neurology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.

出版信息

J Med Invest. 2010 Feb;57(1-2):109-13. doi: 10.2152/jmi.57.109.

DOI:10.2152/jmi.57.109

PMID:20299749

Abstract

In order to investigate the transcallosal effects of repetitive transcranial magnetic stimulation (rTMS), we studied median somatosensory evoked potentials (SEPs) before and after applying monophasic very low-frequency (0.2 Hz) subthreshold rTMS over the right motor cortex. For SEPs, median nerve was stimulated on each side. Sham rTMS served as the control. Twelve healthy subjects participated in this study. After rTMS over the right hemisphere, the amplitude of N34 component in right median SEPs recorded from the left parietal scalp (C3') increased significantly. Other components of right or left median SEPs or those after sham stimulation showed no changes. Monophasic 0.2 Hz subthreshold rTMS over the motor cortex predominantly affected the contralateral SEPs, probably through the transcallosal pathway.

摘要

为了研究重复经颅磁刺激（rTMS）的胼胝体效应，我们在右侧运动皮层施加单相极低频（0.2 Hz）阈下rTMS之前和之后，研究了正中体感诱发电位（SEPs）。对于SEPs，在每一侧刺激正中神经。假rTMS作为对照。12名健康受试者参与了本研究。在右侧半球进行rTMS后，从左侧顶叶头皮（C3'）记录的右侧正中SEPs中N34成分的波幅显著增加。右侧或左侧正中SEPs的其他成分或假刺激后的成分均无变化。运动皮层上的单相0.2 Hz阈下rTMS可能通过胼胝体通路主要影响对侧SEPs。