双侧体感诱发电位在间歇性 theta 爆发重复经颅磁刺激后的变化。
Bilateral somatosensory evoked potentials following intermittent theta-burst repetitive transcranial magnetic stimulation.
机构信息
Department of Kinesiology, University of Waterloo, Waterloo, Canada.
出版信息
BMC Neurosci. 2010 Aug 5;11:91. doi: 10.1186/1471-2202-11-91.
Abstract
BACKGROUND
Intermittent theta-burst stimulation (iTBS) is a form of repetitive transcranial magnetic stimulation that may alter cortical excitability in the primary somatosensory cortex (SI). The present study investigated the effects of iTBS on subcortical and early cortical somatosensory evoked potentials (SEPs) recorded over left, iTBS stimulated SI and the right-hemisphere non-stimulated SI. SEPs were recorded before and at 5, 15, and 25 minutes following iTBS.
RESULTS
Compared to pre-iTBS, the amplitude of cortical potential N20/P25 was significantly increased for 5 minutes from non-stimulated SI and for 15 to 25 minutes from stimulated SI. Subcortical potentials recorded bilaterally remained unaltered following iTBS.
CONCLUSION
We conclude that iTBS increases the cortical excitability of SI bilaterally and does not alter thalamocortical afferent input to SI. ITBS may provide one avenue to induce cortical plasticity in the somatosensory cortex.
摘要
背景
间歇性 theta 爆发刺激（iTBS）是一种重复经颅磁刺激形式，可能会改变初级体感皮层（SI）的皮质兴奋性。本研究调查了 iTBS 对记录于左侧、iTBS 刺激的 SI 和右侧非刺激的 SI 的皮质下和早期皮质体感诱发电位（SEP）的影响。SEP 在 iTBS 之前和之后的 5、15 和 25 分钟进行记录。
结果
与 iTBS 前相比，非刺激 SI 的皮质电位 N20/P25 的振幅在 5 分钟时显著增加，而刺激 SI 的振幅在 15 至 25 分钟时增加。iTBS 后双侧皮质下电位保持不变。
结论
我们得出结论，iTBS 双侧增加 SI 的皮质兴奋性，而不改变丘脑皮质传入到 SI 的输入。iTBS 可能为诱导体感皮层的皮质可塑性提供了一种途径。
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