Department of Anesthesiology, Intensive Care Medicine, Multidisciplinary Pain Centre, Ziekenhuis Oost-Limburg, Genk, Belgium.
Reg Anesth Pain Med. 2010 Mar-Apr;35(2):148-51. doi: 10.1097/aap.0b013e3181d24713.
Occipital neuralgia is a paroxysmal nonthrobbing, stabbing pain in the area of the greater or lesser occipital nerve caused by irritation of these nerves. Although several therapies have been reported, no criterion standard has emerged. This study reports on the results of a prospective trial with 6 months of follow-up in which pulsed radiofrequency treatment of the greater and/or lesser occipital nerve was used to treat this neuralgia.
Patients presenting with clinical findings suggestive of occipital neuralgia and a positive test block of the occipital nerves with 2 mL of local anesthetic underwent a pulsed radiofrequency procedure of the culprit nerves. Mean scores for pain, quality of life, and medication intake were measured 1, 2, and 6 months after the procedure. Pain was measured by the visual analog and Likert scales, quality of life was measured by a modified brief pain questionnaire, and medication intake was measured by a Medication Quantification Scale.
During a 29-month period, 19 patients were included in the study. Mean visual analog scale and median Medication Quantification Scale scores declined by 3.6 units (P = 0.002) and 8 units (P = 0.006), respectively, during 6 months. Approximately 52.6% of patients reported a score of 6 (pain improved substantially) or higher on the Likert scale after 6 months. No complications were reported.
Pulsed radiofrequency treatment of the greater and/or lesser occipital nerve is a promising treatment of occipital neuralgia. This study warrants further placebo-controlled trials.
枕大神经痛是枕大神经或枕小神经受到刺激而引起的一种阵发性非搏动性刺痛,位于枕大神经或枕小神经分布区域。尽管已经报道了几种治疗方法,但没有出现标准的治疗方法。本研究报告了一项前瞻性试验的结果,该试验对 6 个月的随访进行了评估,其中采用脉冲射频治疗枕大神经和/或枕小神经来治疗这种神经痛。
出现临床特征提示为枕大神经痛,且枕大神经或枕小神经局部麻醉阻滞试验阳性的患者接受脉冲射频处理可疑神经。在治疗后 1、2 和 6 个月,对疼痛、生活质量和药物摄入的平均评分进行了测量。疼痛通过视觉模拟评分和 Likert 量表进行测量,生活质量通过改良简短疼痛问卷进行测量,药物摄入通过药物量化量表进行测量。
在 29 个月的时间里,共有 19 名患者纳入研究。在 6 个月的时间里,平均视觉模拟评分和中位数药物量化量表评分分别下降了 3.6 个单位(P = 0.002)和 8 个单位(P = 0.006)。大约 52.6%的患者在治疗后 6 个月后报告 Likert 量表评分达到 6(疼痛显著改善)或更高。未报告任何并发症。
脉冲射频治疗枕大神经和/或枕小神经是治疗枕大神经痛的一种很有前途的方法。本研究需要进一步的安慰剂对照试验。