Mordasini R
Schweiz Med Wochenschr. 1978 Jan 28;108(4):113-9.
Hyperlipoproteinemia is found in about 10--15% of the adult population. There is a strong correlation between elevated total and LDL cholesterol levels, decreased HDL cholesterol values and the incidence of coronary heart disease. Large-scale screening for this strong risk factor should be initiated at an early stage, when possible even in childhood. Dietary treatment is the basis of all lipid-lowering therapy. Lipid-lowering drugs should be given only in addition to a carefully controlled diet. Dietary and drug treatment of hyperlipoproteinemia is discussed.
约10% - 15%的成年人群中存在高脂蛋白血症。总胆固醇和低密度脂蛋白胆固醇水平升高、高密度脂蛋白胆固醇值降低与冠心病发病率之间存在密切关联。对于这一强大的风险因素,应尽早开展大规模筛查,如有可能甚至在儿童期就进行。饮食治疗是所有降脂治疗的基础。降脂药物应仅在严格控制饮食的基础上使用。本文讨论了高脂蛋白血症的饮食和药物治疗。