Endocrinology Service and Research Center and Department of Pediatrics, CHU Sainte-Justine and Université de Montréal, Montréal, Canada.
Department of Obstetrics and Gynecology, CHU Sainte-Justine and Université de Montréal, Montréal, Canada.
J Pediatr. 2010 Jun;156(6):1026-1029. doi: 10.1016/j.jpeds.2010.01.018. Epub 2010 Mar 20.
Hypothyroidism was documented by cordocentesis at 19 weeks in a fetus with non-immune goiter. Intra-amniotic thyroxine was injected at 25 weeks when amniotic fluid volume increased. Psychomotor outcome was normal. We argue that intra-amniotic thyroxine should not be used to treat the hypothyroidism but only to correct the development of polyhydramnios.
胎儿在 19 周时因非免疫性甲状腺肿通过脐带血穿刺术确诊为甲状腺功能减退症。当羊水体积增加时,在 25 周时向羊膜腔内注射甲状腺素。精神运动发育结果正常。我们认为,不应使用羊膜腔内甲状腺素来治疗甲状腺功能减退症,而仅用于纠正羊水过多的发展。