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[社区感染中的处方模式与抗生素使用]

[Prescription patterns and antibiotic use in community-based infections].

作者信息

Del Fiol Fernando de Sá, Lopes Luciane Cruz, Toledo Maria Inês de, Barberato-Filho Silvio

机构信息

Departamento de Farmacologia, Universidade de Campinas, Campinas, SP.

出版信息

Rev Soc Bras Med Trop. 2010 Jan-Feb;43(1):68-72. doi: 10.1590/s0037-86822010000100015.

Abstract

INTRODUCTION

The aim of this study was to find out about the patterns of antibiotic use in the municipality of Sorocaba, through evaluating the reported diagnosis and the therapy used.

METHODS

An evaluation tool was applied among antibiotic users over a 12-month period. Sociodemographic data and information relating to health, diagnosis and therapeutics were gathered in relation to 403 users.

RESULTS

Great present use and the greatest previous use was found in the 0-10 year-old age group (p < 0.05). Infections with lung involvement were the ones most mentioned (p < 0.05) and penicillins were the drugs most used, present in 45.1% of the prescriptions. The mean duration of therapy for otitis (8.9 days) was below the recommendation. For sinusitis, 22% of the prescriptions did not give guidance regarding recommended use (10 days).

CONCLUSIONS

The lack and/or nonuse of therapeutic protocols resulted in great differences in prescription patterns, thereby leading to therapeutic failure and recurrence of infections, which were situations frequently found in this study.

摘要

引言

本研究的目的是通过评估报告的诊断和使用的治疗方法,了解索罗卡巴市抗生素的使用模式。

方法

在12个月的时间里,对抗生素使用者应用了一种评估工具。收集了403名使用者的社会人口统计学数据以及与健康、诊断和治疗相关的信息。

结果

在0至10岁年龄组中发现目前使用抗生素的情况最多,以前使用抗生素的情况也最为普遍(p < 0.05)。提及最多的是伴有肺部受累的感染(p < 0.05),青霉素是使用最多的药物,占处方的45.1%。中耳炎的平均治疗时长(8.9天)低于推荐时长。对于鼻窦炎,22%的处方未给出关于推荐使用时长(10天)的指导。

结论

治疗方案的缺乏和/或未使用导致处方模式存在很大差异,从而导致治疗失败和感染复发,这是本研究中经常出现的情况。

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