Gamma Knife of Spokane, 910 W 5th Ave, Suite 102, Spokane, WA 99204, USA.
World J Surg Oncol. 2010 Mar 22;8:20. doi: 10.1186/1477-7819-8-20.
Approximately 5 million people in America are affected by essential tremors (ET), which are classified as a type of benign movement disorder. This disease manifests as tremors that usually occur in the hands, but they may also be present in the head, face, tongue, and lower limbs. Radiofrequency thalamotomy (RF) and deep brain stimulation (DBS) are common invasive procedures with proven track records that are used to treat ET. Although these procedures have high success rates, they still put patients at risk of potential side effects and are invasive by nature. Thalamotomy using the gamma knife (GK) also produces favorable outcomes in treating tremors, without the complications associated with invasive neurosurgery procedures. This report describes the presenting symptoms and extended treatment outcome for a patient with an advanced case of ET, who received GK thalamotomy treatment six years ago. Because of this non-invasive treatment, she regained the ability to paint and live with an improved quality of life. We also discuss and review the relevant literature regarding the risks and benefits of this treatment modality. GK thalamotomy is one effective option for the treatment of ET, and due to its noninvasive nature, it has a different risk profile than neurosurgery. We suggest that GK thalamotomy should be presented as one viable treatment option to all ET patients, and should be recommended to those who would be best served by less invasive treatment techniques.
美国约有 500 万人受到原发性震颤(ET)的影响,该病被归类为一种良性运动障碍。这种疾病表现为震颤,通常发生在手部,但也可能发生在头部、面部、舌头和下肢。射频丘脑切开术(RF)和深部脑刺激(DBS)是两种常见的具有良好治疗记录的侵入性手术,用于治疗 ET。虽然这些手术成功率高,但仍存在潜在副作用风险,且具有侵入性。伽玛刀(GK)丘脑切开术在治疗震颤方面也有良好的效果,且没有与侵入性神经外科手术相关的并发症。本报告描述了一名 ET 晚期患者的临床表现和延长治疗结果,该患者在六年前接受了 GK 丘脑切开术治疗。由于这种非侵入性治疗,她恢复了绘画能力,生活质量得到了改善。我们还讨论和回顾了关于这种治疗方式的风险和益处的相关文献。GK 丘脑切开术是治疗 ET 的有效方法之一,由于其非侵入性,与神经外科相比,它具有不同的风险特征。我们建议向所有 ET 患者提出 GK 丘脑切开术作为一种可行的治疗选择,并建议那些最适合采用微创治疗技术的患者进行该治疗。