Pfizer Inc., Groton, CT 06340, USA.
Int J Pharm. 2010 Jun 15;392(1-2):107-10. doi: 10.1016/j.ijpharm.2010.03.039. Epub 2010 Mar 20.
Experiments have been conducted to measure the coefficient of rolling resistance (CoRR) of some pharmaceutical tablets and several common materials, such as glass beads and steel ball bearings. CoRR values are required as inputs for discrete element method (DEM) models which can be used to model particulate flows and solid dosage form manufacturing processes. Until now there have been no CoRR data reported for pharmaceutical materials, and thus these new data will help to facilitate more accurate modeling of pharmaceutical systems.
已经进行了实验来测量一些药片和几种常见材料（如玻璃珠和钢球轴承）的滚动阻力系数（CoRR）。CoRR 值是离散元法（DEM）模型所需的输入，该模型可用于模拟颗粒流和固体制剂制造过程。到目前为止，还没有报道过用于药物材料的 CoRR 数据，因此这些新数据将有助于更准确地对药物系统进行建模。
