白血病的造血干细胞移植。
Hematopoietic stem cell transplantation for leukemia.
机构信息
Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Room 1-3750, 9000 Rockville Pike, MSC 1104, Bethesda, MD 20892-1104, USA.
出版信息
Pediatr Clin North Am. 2010 Feb;57(1):1-25. doi: 10.1016/j.pcl.2009.11.005.
Abstract
Leukemia represents the most common pediatric malignancy, accounting for approximately 30% of all cancers in children less than 20 years of age. Most children diagnosed with leukemia are cured without hematopoietic stem cell transplantation (HSCT), but for some high-risk subgroups, allogeneic HSCT plays an important role in their therapeutic approach. The characteristics of these high-risk subgroups and the role of HSCT in childhood leukemias are discussed.
摘要
白血病是最常见的儿科恶性肿瘤，占所有 20 岁以下儿童癌症的约 30%。大多数诊断患有白血病的儿童无需造血干细胞移植（HSCT）即可治愈，但对于某些高危亚组，异基因 HSCT 在其治疗方法中起着重要作用。本文讨论了这些高危亚组的特征以及 HSCT 在儿童白血病中的作用。
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